Bladder cancer Mature results from the KEYNOTE-045 trial were presented at ESMO 2017. The phase 3 study KEYNOTE-045 randomly assigned patients whose urothelial cancer had recurred or progressed after platinum-based chemotherapy, to either pembrolizumab (n=272) or the investigator’s choice of paclitaxel, docetaxel, or vinflunine chemotherapy (n=270). Now the 22.5 months of follow-up data confirmed a significantly longer survival in patients … Read More
ESMO September 2017: Results in study Nivolumab Plus Ipilimumab versus Sunitinib in First-Line Treatment for Advanced or Metastatic RCC
Kidney Cancer Nivolumab Plus Ipilimumab versus Sunitinib in First-Line Treatment for Advanced or Metastatic RCC. Bernard Escudier, Institut Gustave Roussy, Villejuif, France presented the results of the phase III, randomised, open-label CheckMate-214 study evaluating the combination of nivolumab and ipilimumab compared to sunitinib in patients with previously untreated advanced or metastatic RCC. Patients with measurable clear-cell metastatic RCC, Karnofsky performance … Read More